Ma Mansourighiasi, A Nasrollahiomran, M Hashemi, P Rajab Zadekanafi, M Jahangiri Rad Manjili,
Volume 7, Issue 1 (4-2013)
Abstract
Abstract
Background and Objective:Staphylococcusaureus is one of the important factors causing nosocomial infections. Typically 25-30 percent of healthy people carry the bacteria in their anterior nasal cavity. The physicians(50%), nurses (70%) and hospital staff (90%) are the carriers of this bacteria, leading to the infection of inpatients. The emergence of antibiotic-resistant Staphylococcus strains to vancomycin and methicillin has brought about several problems in treatment of the infections caused by Staphylococcus strains. Hence, we aimed to study the frequency of staphylococcus aureus carriers and resistance pattern among medical personnel of the surgical ward in ShahidRajaee hospital, Tonekabon.
Material and Methods: this analytic-descriptive study was conducted on the samples taken from nasal carriage of medical staff of surgical ward (N=120). Antibiotic- resistant of Staphylococcus strains was assessed by antibiogram and disk diffusion (DAD), in accordance with CLSI standards.
Results: of 34 (28.33%) who are nasal carriers of staphylococcus, 12 are over 30 years old and 24 under 30. Based on antibiogram, 1.97% of specimens are sensitive to Gentamicin and Co-trimoxazole, 1.94% to Ciprofloxacin, 2.88% to Vancomycin and 6.20% to Methicillin. In addition, 100% of specimens are resistant to Ampicillin, 1.97% to Penicillin and 2.88% to Amoxicillin. Four isolates areresistant,both to methicillin and vancomycin.
Conclusion:In this study, the spectrum of S. aureus resistant and sensitive strains to some antibiotics is similar to other studies, but a dramatic increase is seen in the rate of MRSA and non-susceptible cases to vancomycin. The Effectiveness of Penicillin, Amoxicillin and Ampicillin is still very low on S. aureus samples.
Key words: Prevalance Resistance Pattern, Staphylococcus aureus, Medical Staff, Nasal Cavity, Tonekabon
Hadi Sedigh Ebrahim-Saraei, Tofigh Yaghoubi , Zeynab Fathalizadeh , Masoumeh Pourmohammadi , Hojat Eftekhari ,
Volume 20, Issue 4 (9-2026)
Abstract
Background: Nosocomial infections are among the most concerning issues affecting hospitalized patients. The present study investigated the frequency of bacterial infections and their antibiotic resistance patterns among patients hospitalized in the dermatology ward.
Methods: This cross-sectional study was conducted among patients admitted to the dermatology ward at Razi Hospital, Rasht, Iran, between 2018 and 2022. The demographic data and clinical characteristics of the 34 patients with bacterial infections were recorded and analyzed. Bacterial isolates were obtained from skin and soft tissue, urinary tract, or bloodstream infections, and the patients' clinical findings and outcomes were recorded.
Results: Thirty-four patients had positive bacterial culture results. The mean age of the patients was 53.56±17.14 years, and 61.8% were female. The urinary tract was the most frequent site of infection. Staphylococcus epidermidis (S. epidermidis) and Klebsiella spp. were the most prevalent isolates. Klebsiella spp. and Escherichia coli (E. coli) were more common in patients aged <56 years and ≥56 years, respectively, and in those hospitalized for ≥13 days and <13 days, respectively. Antibiotic resistance was high among S. epidermidis and Pseudomonas aeruginosa (P. aeruginosa) isolates, both of which showed resistance to all antibiotics.
Conclusion: This study revealed significant patterns of bacterial infection and antibiotic resistance among patients in the dermatology ward. E. coli and Klebsiella spp. predominated in urinary tract infections, whereas skin and soft tissue infections exhibited a more diverse profile.
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