Showing 4 results for Blood Transfusion
Madhusudana Hn, Akriti Kashyap, Sunita Patil, Gurpuneet Basra, Navnath Dighe, Sashindran Vk,
Volume 16, Issue 3 (5-2022)
Abstract
Background and objectives: Intraoperative blood transfusion is a common medical intervention worldwide. Although mostly lifesaving when indicated, inappropriate administration of intraoperative can be potentially life-threatening. The aim of this study was to analyze the most common surgery/invasive procedures requiring intraoperative transfusion and to determine indications for intraoperative transfusion as well as the outcome of the patients after intraoperative transfusion.
Methods: A retrospective review of the electronic database of medical records was done for surgical patients who received intraoperative transfusion from June 2019 to December 2019. Preoperative hemoglobin values, associated comorbidities, and physiological triggers including hypotension and tachycardia were recorded. Descriptive statistics were used to summarize the data.
Results: A total of 36 patients (age range: 9-80 years) were studied. Orthopedic surgeries (53%) were the most common surgeries that required intraoperative transfusion. Preoperative anemia (hemoglobin <10 g/dl) was the predominant reason for intraoperative transfusion. Type 2 diabetes mellitus (36.3%) was the most frequent comorbidity among the cases of intraoperative transfusion. Half the cases received two units of packed red blood cell (pRBC), while 39% of the cases received one unit of pRBC. The remaining 11.1% received more than two units of pRBC. Furthermore, 77.7% of the patients were discharged to home within a week, while 16.6% of the patients were discharged after a prolonged hospital stay (> one week). The remaining 5.5% died in the hospital within a week of the procedure/surgery.
Conclusion: Transfusion practices vary among physicians, hospitals, and countries. The findings highlight that the hospital might be the most important determinant of the number of administered transfusions, with some adopting programs to reduce transfusions for elective surgery.
Aneesha Asok Kumar, Deepak Panasseril Jayapradeep, Gayathri Gangadharan Nair , Sebina Asmi, Ashid Salim,
Volume 17, Issue 5 (9-2023)
Abstract
Background: Blood transfusion is a potentially life-saving procedure that has many consequences and complications. Most of the complications are due to clerical and technical problems. Hence, the proper knowledge and skills of the personnel involved in blood transfusion are critical. Nurses are an integral part of blood transfusion procedures. Our study aimed to evaluate nurses' knowledge about safe blood transfusion practices in a tertiary care center in North Kerala.
Methods: This was a descriptive, cross-sectional study of 113 registered nurses involved in a blood transfusion procedure in a tertiary care center in North Kerala. The knowledge of the nurses was evaluated by using a questionnaire comprising 20 questions, of which 10 questions were about theoretical knowledge and 10 were about practical knowledge. Scores>75%, between 50% and 75%, and <50% were considered as good, fair, and poor knowledge, respectively.
Results: In our study, 44.25% of the nurses showed fair knowledge, and 32.7% had poor knowledge of knowledgebased questions. Moreover, 48.6 % had fair knowledge, and 14.16% had poor knowledge of practice-based questions. No statistically significant association was found between nurses' years of experience and theoretical and practical knowledge. A statistically significant association was found between the place of work and theoretical and practical knowledge. Many of the nurses lacked proper knowledge regarding the key aspects of blood transfusion.
Conclusion: We recommend more training programs to improve the knowledge and skills of the nurses to ensure the quality and safety of blood transfusion.
Yashica Gowda R, Suja Ajoy Kumar, Karthik Srevatsa,
Volume 19, Issue 4 (7-2025)
Abstract
Background: The significance of blood transfusion is best captured by the phrase, "It's not just blood-it's liquid life." However, without proper safety measures, transfusion carries serious risks, including the transmission of highly infectious diseases. Among these, hepatitis B virus infection poses a major public health threat due to its high infectivity, potential for chronic infection, and severe complications. Despite the availability of an effective vaccine, hepatitis B virus remains a persistent challenge in transfusion medicine, underscoring the need for stringent screening and preventive strategies. This study aimed to determine the trend of hepatitis B surface antigen (HBsAg) seropositivity among the blood donor population over five years and its prevalence among voluntary and replacement donors.
Methods: This study was conducted at a licensed blood center of a tertiary care hospital. A retrospective review of blood donor data over five years was extracted. All donated blood was screened for the presence of HBsAg using commercially available ELISA kits. All repeatedly reactive samples were labelled seropositive. The data were analyzed for trends in the prevalence of HBsAg over the study period.
Results: A total of 18,139 healthy donors were screened during the study period. Among them, 11,517 were replacement donors and 6,622 were voluntary donors. The overall prevalence of HBsAg seropositivity was 0.66%, which was higher in replacement blood donors (0.46%). A decline in the incidence of HBsAg among donors was also observed over the five-year study duration.
Conclusion: Promoting and encouraging voluntary blood donation is a simple and effective way to reduce the prevalence of all transfusion-transmitted infections.
Seyed Sadegh Baniaghil , Fardin Balochi , Ereste Kazzak ,
Volume 19, Issue 4 (7-2025)
Abstract
Background: One of the major complications in thalassemia patients is alloimmunization, which occurs when the patient produces antibodies against transfused Red Blood Cells (RBCs). In the present study, the frequency of alloantibodies was investigated in patients with thalassemia major.
Methods: This cross-sectional retrospective study was performed on 99 multi-transfused patients with thalassemia major. An antibody screening test was carried out using a three-cell panel. Positive patients were followed up for antibody identification using an 11-cell panel. The information was finally analyzed using SPSS software version 16.0.
Results: Out of ninety-nine cases, 53 were female (53.53 %) and 46 were male (46.46 %). The patient’s mean age was 29.22±10.46 years with an age range of 2 to 61 years. Only 5.05% (n=5) had developed alloantibodies. The most common alloantibodies were anti-D, anti-E, anti-c, and anti-K. No significant correlation was seen between the presence of alloantibody and age, sex, blood type, and spleen condition.
Conclusion: Antibody production against RBC antigens is a common problem in multi-transfused thalassemia patients. Compatibility between antigens of the Kell and Rh blood group systems in donors and recipients can be one of the useful ways to prevent alloimmunization of blood recipients and the formation of unexpected antibodies against the donor’s red blood cells.
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