Showing 3 results for Kheirollahi
Zahra Roustaeizade, Mohamad Hassan Akhavan Karbassi, Khatereh Kheirollahi, Ehsan Babaei Zarch,
Volume 6, Issue 3 (9-2018)
Abstract
Background and objectives: Recurrent aphthous stomatitis (RAS) is a painful ulcerative lesion and its incidence is 20% in the society. Myrtus communis (myrtex) has been effective in the treatment of RAS. In this study, two different concentrations (2.5% versus 5%) of myrtex extract were evaluated to discover the most effective concentration for the treatment of RAS.
Methods: In this randomized, double-blind clinical trial, 60 patients with RAS were evaluated. Thirty patients used myrtex extract 5% and thirty patients used myrtex extract 2.5% (10 drops on lesion for 20 seconds 5 times per day). The severity of pain and burning sensation experienced by patients were measured by visual analogue scale (VAS) and the size of the lesion was estimated by transparent calibrated grid Data analysis was done by running t-test and repeated measures statistical test.
Results: The mean of the largest RAS diameter before treatment was decreased in both groups 1 day and 7 days after treatment (P-value=0.000); however, these differences were not significant in both groups (P-value =0.401). Furthermore, the severities of pain and burning sensation were decreased in both groups (p-value = 0.000). Nevertheless, this decrease was similar in both groups (P-value = 964).
Conclusion: Treatment with different concentrations of myrtex extract is effective in decreasing RAS diameter, pain, and burning sensation. In addition, the therapeutic efficacy of two different concentrations of myrtex extract (2.5% and 5%) was similar in this regard.
Khatereh Kheirollahi, Seyyed Hossein Hekmati Moghadam, Gooya Kabir, Zhaleh Zare Mehrjardi,
Volume 7, Issue 2 (7-2019)
Abstract
Background and objectives: patients undergoing Chemotherapy are severely susceptible to infections due to a compromised immune system and also their oral cavity is a great place for microorganisms and fungi to grow. The aim of this study was to determine the distribution of different strains of Candida from oral lesions of these patients.
Methods and Materials: This descriptive study was performed on 128 patients undergoing chemotherapy in teaching hospitals of Yazd, which was three weeks pass receiving their first medicine. Oral samples were prepared from swabs and then cultured in Sabouraud dextrose agar culture media for evaluation of yeast growth, colonization, and identification of species. Samples were examined under the microscope and recorded. Finally, the data were analyzed by SPSS17 software, Chi-square, and Man-Whitney tests.
Results:128 patients participated in this study, which included 45 males (35.15%) and 83 females (64.85%) with an average age of 40.16 ± 19.95 years. 84 patients (62.65%) had candida in their oral cavity, of which 79 were candida albicans and 5 were Non-albicans Candida. No significant correlation was found between the type of candidates, type of cancer and the frequency of Candida albicans with the age and sex of the patients (P-value <0.05).
Conclusion: Based on the results of this study, the prevalence of Candida albicans in patients undergoing chemotherapy is higher than Non-albicans Candida. Patients with leukemia are more susceptible to Candida infections.
Mojdeh Khajehlandi, Ali Eyvazi Nasirlu , Hamed Kheirollahi Meidani, Farnaz Seifi-Skishahr , Roghayyeh Fekri, Rasoul Ershadifard,
Volume 12, Issue 1 (10-2024)
Abstract
Background: Insufficiency of omentin-1 and 25-hydroxyvitamin D serum levels is associated with obesity, which is known as a threat to health. Therefore, the aim of the present study was to examine the effect of eight weeks of Pilates exercise on the serum levels of 25-hydroxyvitamin D, omentin-1, and lipid profile in overweight women.
Methods: In the present clinical study, 26 young overweight women were divided (block randomization method) into the Pilates exercise (PT, n= 13) and control group (CG, n= 13). The PT group performed Pilates exercises for eight weeks (three 60-min sessions per week). The movements started from simple and then increased in intensity and complexity based on the Borg index. The CG group had no training session for eight weeks. Blood samples were taken before the first training session and 48 hours after the last training session. Analysis of covariance was used for between-group comparisons.
Results: Findings showed a significant increase in the serum levels of 25-hydroxyvitamin D (p=0.008, SD= 4.78±0.12 ng/ml, effect size= 0.243) and HDL-C (p=0.04, SD= 6.44±1.05 mg/dl, effect size= 0.168), but a significant decrease in HOMA-IR (p=0.001, SD= 1.54±0.09, effect size=0.199), cholesterol (p=0.001, SD= 16.72±3.24 mg/dl, effect size= 0.326), and triglyceride (p=0.001, SD= 2.46±0.07 mg/dl, effect size= 0.209), and no significant change in omentin-1 (p=0.65, SD= 3.01±0.08 ng/ml) and LDL-C (p=0.58, SD= 2.46±0.07 mg/dl) serum levels in the PT group compared to the CG group.
Conclusion: It seems that this type of exercise training may play a critical role in controlling the health parameters and physiological status of the overweight women by having positive effects on serum levels of 25-hydroxyvitamin D and lipid profile, which are affected by body composition, weight, and fat.
